Nature Communications (Aug 2018)

Megahertz data collection from protein microcrystals at an X-ray free-electron laser

  • Marie Luise Grünbein,
  • Johan Bielecki,
  • Alexander Gorel,
  • Miriam Stricker,
  • Richard Bean,
  • Marco Cammarata,
  • Katerina Dörner,
  • Lars Fröhlich,
  • Elisabeth Hartmann,
  • Steffen Hauf,
  • Mario Hilpert,
  • Yoonhee Kim,
  • Marco Kloos,
  • Romain Letrun,
  • Marc Messerschmidt,
  • Grant Mills,
  • Gabriela Nass Kovacs,
  • Marco Ramilli,
  • Christopher M. Roome,
  • Tokushi Sato,
  • Matthias Scholz,
  • Michel Sliwa,
  • Jolanta Sztuk-Dambietz,
  • Martin Weik,
  • Britta Weinhausen,
  • Nasser Al-Qudami,
  • Djelloul Boukhelef,
  • Sandor Brockhauser,
  • Wajid Ehsan,
  • Moritz Emons,
  • Sergey Esenov,
  • Hans Fangohr,
  • Alexander Kaukher,
  • Thomas Kluyver,
  • Max Lederer,
  • Luis Maia,
  • Maurizio Manetti,
  • Thomas Michelat,
  • Astrid Münnich,
  • Florent Pallas,
  • Guido Palmer,
  • Gianpietro Previtali,
  • Natascha Raab,
  • Alessandro Silenzi,
  • Janusz Szuba,
  • Sandhya Venkatesan,
  • Krzysztof Wrona,
  • Jun Zhu,
  • R. Bruce Doak,
  • Robert L. Shoeman,
  • Lutz Foucar,
  • Jacques-Philippe Colletier,
  • Adrian P. Mancuso,
  • Thomas R. M. Barends,
  • Claudiu A. Stan,
  • Ilme Schlichting

DOI
https://doi.org/10.1038/s41467-018-05953-4
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

Read online

The European X-ray free-electron laser (EuXFEL) in Hamburg is the first megahertz (MHz) repetition rate XFEL. Here the authors use lysozyme crystals and microcrystals from jack bean proteins and demonstrate that damage-free high quality data can be collected at a MHz repetition rate.