Nature Communications (Nov 2021)

Plasma virome and the risk of blood-borne infection in persons with substance use disorder

  • Abraham J. Kandathil,
  • Andrea L. Cox,
  • Kimberly Page,
  • David Mohr,
  • Roham Razaghi,
  • Khalil G. Ghanem,
  • Susan A. Tuddenham,
  • Yu-Hsiang Hsieh,
  • Jennifer L. Evans,
  • Kelly E. Coller,
  • Winston Timp,
  • David D. Celentano,
  • Stuart C. Ray,
  • David L. Thomas

DOI
https://doi.org/10.1038/s41467-021-26980-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 7

Abstract

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Spread of bloodborne infections, such as HCV and HIV, is a problem, particularly amongst people who inject drugs (PWID). Here, the authors describe and then confirm in observational PWID cohorts that those with more non-pathogenic viruses in plasma were more likely later to acquire HCV than PWID who had fewer of these non-pathogenic viruses.