Supporting Cells of the Human Olfactory Epithelium Co-Express the Lipid Scramblase TMEM16F and ACE2 and May Cause Smell Loss by SARS-CoV-2 Spike-Induced Syncytia

• Andres Hernandez-Clavijo,
• Kevin Y. Gonzalez-Velandia,
• Uday Rangaswamy,
• Giorgia Guarneri,
• Paolo Boscolo-Rizzo,
• Margherita Tofanelli,
• Nicoletta Gardenal,
• Remo Sanges,
• Michele Dibattista,
• Giancarlo Tirelli,
• Anna Menini

Affiliations

Andres Hernandez-Clavijo

Neuroscience Area, SISSA, Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

Kevin Y. Gonzalez-Velandia

Neuroscience Area, SISSA, Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

Uday Rangaswamy

Neuroscience Area, SISSA, Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

Giorgia Guarneri

Neuroscience Area, SISSA, Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

Paolo Boscolo-Rizzo

Department of Medical, Surgical and Health Sciences, Section of Otolaryngology, University of Trieste, Trieste, Italy

Margherita Tofanelli

Department of Medical, Surgical and Health Sciences, Section of Otolaryngology, University of Trieste, Trieste, Italy

Nicoletta Gardenal

Department of Medical, Surgical and Health Sciences, Section of Otolaryngology, University of Trieste, Trieste, Italy

Remo Sanges

Neuroscience Area, SISSA, Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

Michele Dibattista

Department of Basic Medical Sciences, Neuroscience and Sensory Organs, University of Bari A. Moro, Bari, Italy

Giancarlo Tirelli

Department of Medical, Surgical and Health Sciences, Section of Otolaryngology, University of Trieste, Trieste, Italy

Anna Menini

Neuroscience Area, SISSA, Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy