Frontiers in Physiology (Oct 2020)

Effects of Blood Flow Restriction on Leukocyte Profile and Muscle Damage

  • Leandro dos Santos,
  • Leandro dos Santos,
  • Michely V. Andreatta,
  • Victor M. Curty,
  • Wena Dantas Marcarini,
  • Lucas G. Ferreira,
  • Valerio G. Barauna

DOI
https://doi.org/10.3389/fphys.2020.572040
Journal volume & issue
Vol. 11

Abstract

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Muscle damage affects the blood leukocyte profile. Resistance exercise (RE) with blood flow restriction (BFR) attenuates exercise-induced muscle damage (EIMD).PurposeTo evaluate muscle damage and the leukocyte profile in response to RE+BFR and to compare with high intensity RE.MethodsTwenty volunteers performed the RE in the leg press apparatus in the following groups: RE80, 80% of 1RM (3 × until concentric muscle failure); RE40+BFR, 40% of 1RM with BFR (same total work of RE80 group). The BFR applied was 80% of the total occlusion pressure.ResultsThere were no differences in the blood leukocyte profile among groups despite the lower exercise-induced muscle damage (EIMD) in the RE40+BFR group (RE80: 10.07 ± 2.67 vs. RE40+BFR: 8.25 ± 0.96; cell × 103/mm3). Both groups showed leukocytosis (RE80: 7.59 ± 1.48 vs. 10.07 ± 2.67 and RE40+BFR: 6.57 ± 1.50 vs. 8.25 ± 0.96; cell × 103/mm3) and lymphocytosis (RE80: 2.48 ± 0.83 vs. 3.65 ± 1.31 and RE40+BFR: 2.22 ± 0.23 vs. 3.03 ± 0.65; cell × 103/mm3) immediately after exercise. Leukocytosis (ES 1.12 vs. ES 1.33) and lymphocytosis (ES 1.11 vs. ES 1.76) was greater in the RE40+BFR group.ConclusionRE associated with BFR was accompanied by a greater leukocytosis and lymphocytosis immediately after exercise, with no difference in neutrophils. This leukocyte blood profile may be related to less muscle damage, as well as faster muscle recovery after 24 and 48 h post-exercise.

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