BMJ Open (Jan 2024)

Access to cancer clinical trials for racialised older adults: an equity-focused rapid scoping review protocol

  • Martine T E Puts,
  • Tina Hsu,
  • Caroline Mariano,
  • Shabbir M H Alibhai,
  • Sabrina T Wong,
  • David Dawe,
  • Jacqueline L Bender,
  • Lorelei Newton,
  • Rouhi Fazelzad,
  • Aisha Lofters,
  • Vivian Li,
  • Schroder Sattar,
  • Kenneth Noel,
  • Kristin Haase,
  • Sara Durbano,
  • Jennifer A Bell,
  • Jackie Manthorne

DOI
https://doi.org/10.1136/bmjopen-2023-074191
Journal volume & issue
Vol. 14, no. 1

Abstract

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Background The intersection of race and older age compounds existing health disparities experienced by historically marginalised communities. Therefore, racialised older adults with cancer are more disadvantaged in their access to cancer clinical trials compared with age-matched counterparts. To determine what has already been published in this area, the rapid scoping review question are: what are the barriers, facilitators and potential solutions for enhancing access to cancer clinical trials among racialised older adults?Methods We will use a rapid scoping review methodology in which we follow the six-step framework of Arksey and O’Malley, including a systematic search of the literature with abstract and full-text screening to be conducted by two independent reviewers, data abstraction by one reviewer and verification by a second reviewer using an Excel data abstraction sheet. Articles focusing on persons aged 18 and over who identify as a racialised person with cancer, that describe therapies/therapeutic interventions/prevention/outcomes related to barriers, facilitators and solutions to enhancing access to and equity in cancer clinical trials will be eligible for inclusion in this rapid scoping review.Ethics and dissemination All data will be extracted from published literature. Hence, ethical approval and patient informed consent are not required. The findings of the scoping review will be submitted for publication in a peer-reviewed journal and presentation at international conferences.