Diagnostics (May 2024)

Advanced MRI Techniques: Diagnosis and Follow-Up of Multiple Sclerosis

  • Riccardo Nistri,
  • Antonio Ianniello,
  • Valeria Pozzilli,
  • Costanza Giannì,
  • Carlo Pozzilli

DOI
https://doi.org/10.3390/diagnostics14111120
Journal volume & issue
Vol. 14, no. 11
p. 1120

Abstract

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Brain and spinal cord imaging plays a pivotal role in aiding clinicians with the diagnosis and monitoring of multiple sclerosis. Nevertheless, the significance of magnetic resonance imaging in MS extends beyond its clinical utility. Advanced imaging modalities have facilitated the in vivo detection of various components of MS pathogenesis, and, in recent years, MRI biomarkers have been utilized to assess the response of patients with relapsing–remitting MS to the available treatments. Similarly, MRI indicators of neurodegeneration demonstrate potential as primary and secondary endpoints in clinical trials targeting progressive phenotypes. This review aims to provide an overview of the latest advancements in brain and spinal cord neuroimaging in MS.

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