BMC Genomics (Dec 2012)

A genome-wide scan of selective sweeps in two broiler chicken lines divergently selected for abdominal fat content

  • Zhang Hui,
  • Wang Shou-Zhi,
  • Wang Zhi-Peng,
  • Da Yang,
  • Wang Ning,
  • Hu Xiao-Xiang,
  • Zhang Yuan-Dan,
  • Wang Yu-Xiang,
  • Leng Li,
  • Tang Zhi-Quan,
  • Li Hui

DOI
https://doi.org/10.1186/1471-2164-13-704
Journal volume & issue
Vol. 13, no. 1
p. 704

Abstract

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Abstract Background Genomic regions controlling abdominal fatness (AF) were studied in the Northeast Agricultural University broiler line divergently selected for AF. In this study, the chicken 60KSNP chip and extended haplotype homozygosity (EHH) test were used to detect genome-wide signatures of AF. Results A total of 5357 and 5593 core regions were detected in the lean and fat lines, and 51 and 57 reached a significant level (PRB1, BBS7, MAOA, MAOB, EHBP1, LRP2BP, LRP1B, MYO7A, MYO9A and PRPSAP1, were detected. These genes may be important for AF deposition in chickens. Conclusions We provide a genome-wide map of selection signatures in the chicken genome, and make a contribution to the better understanding the mechanisms of selection for AF content in chickens. The selection for low AF in commercial breeding using this information will accelerate the breeding progress.

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