The Correlation of the IETA Ultrasound Score with the Histopathology Results for Women with Abnormal Bleeding in Western Romania
Alexandru Marius Furau,
Mirela Marioara Toma,
Cringu Ionescu,
Cristian Furau,
Simona Bungau,
Mihai Dimitriu,
Delia Mirela Tit,
Gheorghe Furau,
Izabella Petre,
Marius Craina
Affiliations
Alexandru Marius Furau
Department of Oncology, “Vasile Goldis” Western University of Arad, 310414 Arad, Romania
Mirela Marioara Toma
Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania
Cringu Ionescu
Clinical Department 13, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 030167 Bucharest, Romania
Cristian Furau
Department of Pathophysiology, Faculty of Medicine, “Vasile Goldis” Western University of Arad, 310414 Arad, Romania
Simona Bungau
Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania
Mihai Dimitriu
Clinical Department 13, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 030167 Bucharest, Romania
Delia Mirela Tit
Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania
Gheorghe Furau
Department of Obstetrics and Gynecology, Emergency Clinical County Hospital of Arad, 310037 Arad, Romania
Izabella Petre
Department of Obstetrics and Gynecology, Faculty of Medicine and Pharmacy, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Marius Craina
Department of Obstetrics and Gynecology, Faculty of Medicine and Pharmacy, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
In the early differential diagnosis of endometrial cancer (EC), decisive and mandatory histological aspects are considered, in addition to obvious clinical manifestations. In addition, sonographic aspects are characteristic in relation to the stage, degree, and histological types of identified cancer. This bi-center retrospective observational study included 594 women with abnormal uterine bleeding outside pregnancy, for which a biopsy was performed in the Obstetrics and Gynecology Departments of the Emergency County Hospitals of Arad and Timis Counties, Romania, between 2015 and 2019. Most of the cases were represented by EC or endometrial hyperplasia (EH). Of the 594 cases, 25.5% (n = 153) were EC at women aged between 41 and 85 years. High International Endometrial Tumor Analysis (IETA) scores (3, 4) were associated with a relative risk of 2.9335 compared with other endometrial lesions (95% CI 2.3046 to 3.734, p < 0.0001, NNT 1.805). Histological aspects and pelvic ultrasound using IETA scores represent valuable noninvasive assets in diagnosing and differentiating endometrial cancer from benign uterine pathology.
