Frontiers in Neurology (Oct 2023)
Predicting the progression of chronic subdural hematoma based on skull density
- Weijian Yang,
- Weijian Yang,
- Weijian Yang,
- Weijian Yang,
- Weijian Yang,
- Qifang Chen,
- Qifang Chen,
- Qifang Chen,
- Qifang Chen,
- Qifang Chen,
- Haijun Yao,
- Haijun Yao,
- Haijun Yao,
- Haijun Yao,
- Haijun Yao,
- Jun Zhang,
- Jun Zhang,
- Jun Zhang,
- Jun Zhang,
- Jun Zhang,
- Quan Zhang,
- Quan Zhang,
- Quan Zhang,
- Quan Zhang,
- Quan Zhang,
- Jiang Fang,
- Jiang Fang,
- Jiang Fang,
- Jiang Fang,
- Jiang Fang,
- Gang Wu,
- Gang Wu,
- Gang Wu,
- Gang Wu,
- Gang Wu,
- Jin Hu,
- Jin Hu,
- Jin Hu,
- Jin Hu,
- Jin Hu
Affiliations
- Weijian Yang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Weijian Yang
- National Center for Neurological Disorders, Shanghai, China
- Weijian Yang
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Weijian Yang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Weijian Yang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Qifang Chen
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Qifang Chen
- National Center for Neurological Disorders, Shanghai, China
- Qifang Chen
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Qifang Chen
- Neurosurgical Institute of Fudan University, Shanghai, China
- Qifang Chen
- Department of Nursing, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Haijun Yao
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Haijun Yao
- National Center for Neurological Disorders, Shanghai, China
- Haijun Yao
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Haijun Yao
- Neurosurgical Institute of Fudan University, Shanghai, China
- Haijun Yao
- Department of Neurosurgery and Neurocritical Care, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Jun Zhang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Jun Zhang
- National Center for Neurological Disorders, Shanghai, China
- Jun Zhang
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Jun Zhang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Jun Zhang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Quan Zhang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Quan Zhang
- National Center for Neurological Disorders, Shanghai, China
- Quan Zhang
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Quan Zhang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Quan Zhang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Jiang Fang
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Jiang Fang
- National Center for Neurological Disorders, Shanghai, China
- Jiang Fang
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Jiang Fang
- Neurosurgical Institute of Fudan University, Shanghai, China
- Jiang Fang
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Gang Wu
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Gang Wu
- National Center for Neurological Disorders, Shanghai, China
- Gang Wu
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Gang Wu
- Neurosurgical Institute of Fudan University, Shanghai, China
- Gang Wu
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- Jin Hu
- Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
- Jin Hu
- National Center for Neurological Disorders, Shanghai, China
- Jin Hu
- Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China
- Jin Hu
- Neurosurgical Institute of Fudan University, Shanghai, China
- Jin Hu
- Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
- DOI
- https://doi.org/10.3389/fneur.2023.1279292
- Journal volume & issue
-
Vol. 14
Abstract
ObjectiveThe objective of this study was to investigate potential correlations between skull density and the progression of chronic subdural hematoma (CSDH).MethodsPatients with unilateral CSDH were retrospectively enrolled between January 2018 and December 2022. Demographic and clinical characteristics, as well as hematoma and skull density (Hounsfield unit, Hu), were collected and analyzed.ResultsThe study enrolled 830 patients with unilateral CSDH until the resolution of the CDSH or progressed with surgical treatment. Of the total, 488 patients (58.80%) necessitated surgical treatment. The study identified a significant correlation between the progression of CSDH and three variables: minimum skull density (MiSD), maximum skull density (MaSD), and skull density difference (SDD) (p < 0.001). Additionally, in the multivariable regression analysis, MiSD, MaSD, and SDD were independent predictors of CSDH progression. The MiSD + SDD model exhibited an accuracy of 0.88, as determined by the area under the receiver operating characteristic curve, with a sensitivity of 0.77 and specificity of 0.88. The model’s accuracy was validated through additional analysis.ConclusionThe findings suggest a significant correlation between skull density and the CSDH progression.
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