Nickel-catalyzed switchable 1,3-dienylation and enantioselective allenylation of phosphine oxides

Jiayin Zhang; Xihao Chang; Xianghong Xu; Hongyi Wang; Lingzi Peng; Chang Guo

doi:10.1038/s41467-022-34764-x

Nature Communications (Nov 2022)

Nickel-catalyzed switchable 1,3-dienylation and enantioselective allenylation of phosphine oxides

Jiayin Zhang,
Xihao Chang,
Xianghong Xu,
Hongyi Wang,
Lingzi Peng,
Chang Guo

Affiliations

Jiayin Zhang: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
Xihao Chang: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
Xianghong Xu: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
Hongyi Wang: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
Lingzi Peng: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
Chang Guo: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China

DOI: https://doi.org/10.1038/s41467-022-34764-x
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

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Asymmetric catalytic methods for the divergent construction of phosphoryl derivatives are not widely available. Here, the authors show nickel-catalyzed dienylation and enantioselective allenylation of phosphine oxides with high chemo-, regio-, and enantioselectivity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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