Ultra-sensitive non-enzymatic amperometric glucose sensors based on silver nanowire/graphene hybrid three-dimensional nanostructures

Abstract

Ultra-sensitive amperometric glucose sensors were developed by the synergistic combination of one-dimensional silver nanowires (Ag-NWs) and two-dimensional graphene sheets in the form of highly porous three-dimensional nano-structures (3D NSs). To achieve this, a simple hydrothermal sol-gel technique was applied by establishing covalent crosslinks. With a high specific surface area of 119.3 m2 g−1, the developed Ag-NW/graphene hybrid 3D NS-based glucose sensors exhibited a high sensitivity of 1249.1 µA mM−1 cm−2. To the best of our knowledge, this high sensitivity has not been achieved to date in the area of Ag/graphene hybrid-based glucose sensors. The results of this study will be an important step toward the development of electro-catalytic electrodes in bio-sensors.