How narrow-band and broad-band uvb irradiation influences the immunohistochemistry analyses of experimental animals’ skin – a comparative study. Part II

Abstract

This is the second part of the artcle series impact narrow-band UVB radiation (NB-UVB) and broad-band UVB radiation (BB-UVB) on experimental animals’ skin (white Wistar female rats). The aim of this comparative study was immunohistochemistry analyses containing expression of p53 protein. Expression of p53 protein was performed on two experimental groups. One – exposed to NB-UVB; the other – exposed to BB-UVB radiation. The results indicate that p53 protein takes an active part in the process of apoptosis that is induced by both NB-UVB and BB-UVB. The results showed an increase in p53 expressing cells following BB-UVB than NB-UVB phototherapy.

Keywords

• narrow-band UVB