Determining Risk Factors of Postoperative Delirium in Patients Undergoing Liver Transplantation [Letter]

Abstract

Zhao-Jing Xue, Yi Cheng, Fu-Shan Xue Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Fu-Shan XueDepartment of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, NO. 95 Yong-An Road, Xi-Cheng District, Beijing 100050, People’s Republic of ChinaTel [phone]Fax [phone]Email [email protected] In the recent article of Chen et al1 determining the risk factors for postoperative delirium (POD) in patients undergoing liver transplantation, the multivariate logistic regression analysis showed that preoperative ammonia ≥46 μmol/L, Model for End-Stage Liver Disease score ≥15, hepatic encephalopathy, anhepatic period, and aspartate aminotransferase at the first postoperative day were the independent risk factors for POD. The findings of this study have potential clinical implications, but there are several issues in methodology that need further clarification.   View the original paper by Chen and colleagues  

Keywords

• risk factors
• liver transplantation
• postoperative delirium