Retroperitoneal tumors: a case series and literature review

Abstract

Retroperitoneal tumors present significant diagnostic challenges. These tumors can either originate from retroperitoneal tissues or invade the retroperitoneum secondarily. While occurrence of benign lesions is observed, malignant tumors are more prevalent. The clinical presentation varies greatly depending on the tumor size, extent, and involvement of the surrounding tissues, making diagnosis difficult. Given the heterogeneous composition of the tumors, establishing a definitive diagnosis is challenging. Histopathology remains the gold standard technique for studying and analyzing these tumors, with immunohistochemistry being an important tool for confirming the diagnosis. Thus, we describe our experience with a series of four cases of rare retroperitoneal tumors, all of which were surgically resected and subjected to histopathological and immunohistochemical analyses.

Keywords

• adrenocortical carcinoma; granulosa cell tumor; retroperitoneal tumors; teratoma; wilms tumor