Dynamics of ECG indicators in patients with chronic thromboembolic pulmonary hypertension after transluminal pulmonary balloon angioplasty

Abstract

Relevance. Chronic thromboembolic pulmonary hypertension is a precapillary form of pulmonary hypertension that develops as a result of the obstruction of the pulmonary arteries by thrombotic masses. Balloon pulmonary angioplasty is an alternative method of treatment of inoperable CTEPH that has demonstrated hemodynamic and clinical effects. In this study we evaluated the relationship between the improvement in hemodynamic and functional status and ECG in patients with CTEPH who underwent BPA treatment. Materials and methods. In 15 patients with CTEPH, we examined the hemodynamic data before and 1 year after BPA. In addition, the sequential ECG findings for right ventricular hypertrophy (RVH) were assessed. Results. There was a significant decrease in all important hemodynamic parameters. Predictors of the improvement in mean PAP were the amplitudes of the S waves in lead V1 and R in lead V5. The width of the QRS complex and the amplitude of the P wave in lead II were identified as significant factors influencing the degree of improvement in the mean PAP. Normalization (

Keywords

• pulmonary hypertension
• electrocardiography
• chronic thromboembolic pulmonary hypertension
• transluminal balloon angioplasty
• thrombendarterectomy