Mechanistic basis for maintenance of CHG DNA methylation in plants

Jian Fang; Jianjun Jiang; Sarah M. Leichter; Jie Liu; Mahamaya Biswal; Nelli Khudaverdyan; Xuehua Zhong; Jikui Song

doi:10.1038/s41467-022-31627-3

Nature Communications (Jul 2022)

Mechanistic basis for maintenance of CHG DNA methylation in plants

Jian Fang,
Jianjun Jiang,
Sarah M. Leichter,
Jie Liu,
Mahamaya Biswal,
Nelli Khudaverdyan,
Xuehua Zhong,
Jikui Song

Affiliations

Jian Fang: Department of Biochemistry, University of California
Jianjun Jiang: Laboratory of Genetics, University of Wisconsin-Madison
Sarah M. Leichter: Laboratory of Genetics, University of Wisconsin-Madison
Jie Liu: Wisconsin Institute for Discovery, University of Wisconsin-Madison
Mahamaya Biswal: Department of Biochemistry, University of California
Nelli Khudaverdyan: Department of Biochemistry, University of California
Xuehua Zhong: Laboratory of Genetics, University of Wisconsin-Madison
Jikui Song: Department of Biochemistry, University of California

DOI: https://doi.org/10.1038/s41467-022-31627-3
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

Read online

In plants, DNA methylation in the CHG context is maintained by the CMT3 chromomethylases. Here the authors provide a structure-function characterization of a maize CMT3 ortholog to show how recognition of histone modifications stimulate DNA methylation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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