18-ACUTE ERYTHRO-LEUKEMIA (DI GUGLIELMO SYNDROME) IN A YOUNG ADULT IN BASRAH CITY

Abstract

Introduction Giovanni Di Guglielmo first described erythroleukemia, a leukemia composed of purely erythrocytic precursors in 1926, and the disorder is often still referred to as acute Di Guglielmo syndrome. It is classified as an M6 subtype of acute myelogenous leukemia (AML) in the French- American-British (FAB) classification system based on morphologic and cytochemical criteria1a. Acute erythroleukemia accounts for 3-5% of all de novo AMLs and 20-30% of secondary leukemias. It is very rare in children. The incidence of erythroleukemia increases in people older than 50 years2 Mazzella et al (2000) described 2 peaks, one in the seventh decade of life and a second, smaller peak in the fourth decade of life.

Keywords

• leukemia
• guglielmoh saeed