International Journal of Endocrinology (Jan 2025)

Association of Sleep Duration With Serum Estradiol Concentrations Among American Men and Women: Evidence From NHANES 2013–2016

  • Zhisheng Zhu,
  • Shiquan Wu,
  • Xingong Lin,
  • Chaoyang Wang,
  • Xianying Zhou

DOI
https://doi.org/10.1155/ije/7863420
Journal volume & issue
Vol. 2025

Abstract

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Conclusion: The lack of significant associations between sleep duration and serum estradiol concentrations indicates that sleep duration may not influence estradiol levels in the general population of American men and women. These results underscore the importance of continued research into how sleep influences hormonal balance. However, it is important to note that the NHANES data we used are from a cross-sectional study, which cannot establish a causal relationship between sleep duration and serum estradiol. Future studies should investigate additional factors, such as genetic predispositions, lifestyle habits, and environmental influences, that may modulate the relationship between sleep and hormone levels.