Nature Communications (Feb 2021)

An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning

  • Chi-Long Chen,
  • Chi-Chung Chen,
  • Wei-Hsiang Yu,
  • Szu-Hua Chen,
  • Yu-Chan Chang,
  • Tai-I Hsu,
  • Michael Hsiao,
  • Chao-Yuan Yeh,
  • Cheng-Yu Chen

DOI
https://doi.org/10.1038/s41467-021-21467-y
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Deep learning for digital pathology is hindered by the extremely high spatial resolution of whole slide images (WSIs), which requires researchers to adopt patch-based methods and laborious free-hand contouring. Here, the authors develop a whole-slide training method to classify types of lung cancers using slide-level diagnoses with deep learning.