Cryptococcus granuloma mimicking local progressed tumor after cryoablation of renal cell carcinoma: A case report

Hikari Fukui, MD; Masashi Fujimori, MD, PhD; Takashi Yamanaka, MD; Naritaka Matsushita, MD; Seiya Kishi, MD; Chisami Nagata, MD; Yuki Omori, MD; Kouhei Nishikawa, MD, PhD; Hiroto Yuasa, MD; Hajime Sakuma, MD, PhD

Radiology Case Reports (Sep 2022)

Cryptococcus granuloma mimicking local progressed tumor after cryoablation of renal cell carcinoma: A case report

Hikari Fukui, MD,
Masashi Fujimori, MD, PhD,
Takashi Yamanaka, MD,
Naritaka Matsushita, MD,
Seiya Kishi, MD,
Chisami Nagata, MD,
Yuki Omori, MD,
Kouhei Nishikawa, MD, PhD,
Hiroto Yuasa, MD,
Hajime Sakuma, MD, PhD

Affiliations

Hikari Fukui, MD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Masashi Fujimori, MD, PhD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan; Corresponding author.
Takashi Yamanaka, MD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Naritaka Matsushita, MD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Seiya Kishi, MD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Chisami Nagata, MD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Yuki Omori, MD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Kouhei Nishikawa, MD, PhD: Department of Nephro-Urologic Surgery and Andrology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Hiroto Yuasa, MD: Department of Pathology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Hajime Sakuma, MD, PhD: Department of Radiology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan

Journal volume & issue: Vol. 17, no. 9
pp. 3419 – 3424

Abstract

Read online

Infectious granulomas arising in the kidney are rare. However, there are few reports regarding renal granulomas, such as xanthogranulomatous pyelonephritis, sarcoidosis, malakoplakia, and tuberculosis. Here, we report a case of cryptococcal granuloma resembling a locally progressed tumor after percutaneous cryotherapy for renal cell carcinoma. A male patient in his 80s with rheumatoid arthritis underwent computed tomography (CT)-guided cryoablation for biopsy-proven papillary renal cell carcinoma. Follow-up contrast-enhanced CT imaging obtained 4 months after ablation confirmed an enhanced mass on the edge of the ablation zone. There were no symptoms related to the mass. This mass was radiologically diagnosed as local tumor progression and treated with repeated cryoablation. Percutaneous biopsy of the mass was performed immediately after the second cryoablation, and the mass was pathologically diagnosed as granuloma related to Cryptococcus infection. The patient was administered antifungal fluconazole for 1 year with a good outcome.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

About the journal

Abstract

Keywords