The Estrogen Receptor Joins Other Cancer Biomarkers as a Predictor of Outcome

Kimberly K. Leslie; Kristina W. Thiel; Henry D. Reyes; Shujie Yang; Yuping Zhang; Matthew J. Carlson; Nirmala S. Kumar; Donghai D. Dai

doi:10.1155/2013/479541

Obstetrics and Gynecology International (Jan 2013)

The Estrogen Receptor Joins Other Cancer Biomarkers as a Predictor of Outcome

Kimberly K. Leslie,
Kristina W. Thiel,
Henry D. Reyes,
Shujie Yang,
Yuping Zhang,
Matthew J. Carlson,
Nirmala S. Kumar,
Donghai D. Dai

Affiliations

Kimberly K. Leslie: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Kristina W. Thiel: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Henry D. Reyes: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Shujie Yang: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Yuping Zhang: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Matthew J. Carlson: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Nirmala S. Kumar: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Donghai D. Dai: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA

DOI: https://doi.org/10.1155/2013/479541
Journal volume & issue: Vol. 2013

Abstract

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Endometrial cancer, the most common gynecologic malignancy in the United States, is on the rise, and survival is worse today than 40 years ago. In order to improve the outcomes, better biomarkers that direct the choice of therapy are urgently needed. In this review, we explore the estrogen receptor as the most studied biomarker and the best predictor for response for endometrial cancer reported to date.

Published in Obstetrics and Gynecology International

ISSN: 1687-9589 (Print); 1687-9597 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Gynecology and obstetrics
Website: https://onlinelibrary.wiley.com/journal/8272

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