Clusterin mRNA silencing reduces cell proliferation, inhibits cell migration, and increases CCL5 expression in SW480, SW620, and Caco2 cells

Abstract

This study aimed to investigate the effects of specific gene silencing in colorectal cancer cells. Clusterin protein was found in the serum samples of colorectal cancer patients infected with Schistosoma mansoni previously.

Keywords

• ccl5 mrna expression
• clusterin mrna silencing
• colorectal cancer cells
• migration inhibition
• proliferation reduction
• ccl5 mrna ekspresyonu
• clusterin mrna susturma
• kolorektal kanser hücreleri
• migrasyon inhibisyonu
• proliferasyon azalması