Journal of Cutaneous Immunology and Allergy (Feb 2021)
A case of anti‐OJ antibody‐positive polymyositis with marked muscle involvement and interstitial lung disease
Abstract
Abstract An 83‐year‐old man with muscle involvement and interstitial lung disease (ILD) was diagnosed with anti‐OJ antibody (Ab)‐positive polymyositis (PM). He did not have Raynaud's phenomenon, heliotrope rash, Gottron's sign, fever, arthralgia, or mechanic's hand. A literature review of 21 anti‐OJ Ab‐positive patients described that the diagnoses were as follows: 10 with PM, five with dermatomyositis, five with ILD, and 1 with overlap syndrome of PM and rheumatoid arthritis. Myositis was observed in 16, ILD in 19, and skin rash in 5. Physicians need to be aware of the existence of patients with anti‐OJ Ab who have myositis and ILD.
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