Recombinant hexon protein as a new bovine adenovirus type 3 subunit vaccine candidate

Abstract

Bovine adenovirus (BAdV) type 3 causes respiratory and gastroenteric diseases of varying severity in cattle, particularly newborn calves. Trials have been conducted of a vaccination against the diseases caused by BAdV using both modified live-virus and inactivated-virus preparations in cattle, but no commercial BAdV-3 vaccine has yet reached the market. Therefore, there is an urgent need to develop new, safe, and effective vaccines against BAdV-3.

Keywords

• bovine adenovirus type 3
• hexon
• recombinant protein
• subunit
• vaccine.