Molecules (Jan 2002)

Thirteen New Xanthone Derivatives from Calophyllum caledonicum (Clusiaceae)

  • Pascal Richomme,
  • Jean Bruneton,
  • Denis Séraphin,
  • Thierry Sévenet,
  • Marc Litaudon,
  • Anne-Emmanuelle Hay,
  • Cécile Morel

DOI
https://doi.org/10.3390/70100038
Journal volume & issue
Vol. 7, no. 1
pp. 38 – 50

Abstract

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An EtOAc extract of the stem bark of Calophyllum caledonicum (Clusiaceae) yielded thirteen new hydroxylated and/or prenylated xanthone derivatives, namely 5-hydroxy-8-methoxyxanthone (1), 3,5-dihydroxy-1,2-dimethoxyxanthone (2), 1,8-dihydroxy-6,7-dimethoxyxanthone (3), 5,7-dihydroxy-2,6-dimethoxyxanthone (4), 6,8-dihydroxy-3,7-dimethoxy-xanthone (5), 2,5,6,7,8-pentahydroxyxanthone (6), 1,3,8-trihydroxy-5,7-dimethoxyxanthone (7) and according to a previously adopted nomenclature [3], caledonixanthone G-L. (8-13). The structural elucidation of 1-13 were mainly established on the basis of 1D and 2D NMR and HRMS spectroscopic analysis.

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