Frontiers in Computer Science (Jan 2021)

Pauses for Detection of Alzheimer’s Disease

  • Jiahong Yuan,
  • Xingyu Cai,
  • Yuchen Bian,
  • Zheng Ye,
  • Kenneth Church

DOI
https://doi.org/10.3389/fcomp.2020.624488
Journal volume & issue
Vol. 2

Abstract

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Pauses, disfluencies and language problems in Alzheimer’s disease can be naturally modeled by fine-tuning Transformer-based pre-trained language models such as BERT and ERNIE. Using this method with pause-encoded transcripts, we achieved 89.6% accuracy on the test set of the ADReSS (Alzheimer’s Dementia Recognition through Spontaneous Speech) Challenge. The best accuracy was obtained with ERNIE, plus an encoding of pauses. Robustness is a challenge for large models and small training sets. Ensemble over many runs of BERT/ERNIE fine-tuning reduced variance and improved accuracy. We found that um was used much less frequently in Alzheimer’s speech, compared to uh. We discussed this interesting finding from linguistic and cognitive perspectives.

Keywords