Children (Dec 2021)

Improved Less Invasive Surfactant Administration Success in Preterm Infants after Procedure Standardization

  • Björn Liebers,
  • Chinedu Ulrich Ebenebe,
  • Monika Wolf,
  • Martin Ernst Blohm,
  • Eik Vettorazzi,
  • Dominique Singer,
  • Philipp Deindl

DOI
https://doi.org/10.3390/children8121145
Journal volume & issue
Vol. 8, no. 12
p. 1145

Abstract

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Less invasive surfactant administration (LISA) has been introduced at our tertiary Level IV perinatal center since 2016 with an unsatisfactory success rate, which we attributed to an inconsistent, non-standardized approach and ambiguous patient inclusion criteria. This study aimed to improve the LISA success rate to at least 75% within 12 months by implementing a highly standardized LISA approach combined with team training. The Plan Do Study Act method of quality improvement was used for this initiative. Baseline assessment included a review of patient medical records 12 months before the intervention regarding patient characteristics, method success rate, respiratory, and adverse outcomes. A multi-professional team developed a standardized LISA approach and a training program including an educational film, checklists, pocket cards, and team briefings. Twenty-one preterm infants received LISA before and 24 after the intervention. The mean LISA success rate improved from 62% before the intervention to 92% (p = 0.029) after the intervention. Implementing a highly standardized LISA approach and multi-professional team training significantly improved the methods’ success rate.

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