Communications Biology (Jan 2023)
Murine breast cancers disorganize the liver transcriptome in a zonated manner
- Alexis Vandenbon,
- Rin Mizuno,
- Riyo Konishi,
- Masaya Onishi,
- Kyoko Masuda,
- Yuka Kobayashi,
- Hiroshi Kawamoto,
- Ayako Suzuki,
- Chenfeng He,
- Yuki Nakamura,
- Kosuke Kawaguchi,
- Masakazu Toi,
- Masahito Shimizu,
- Yasuhito Tanaka,
- Yutaka Suzuki,
- Shinpei Kawaoka
Affiliations
- Alexis Vandenbon
- Laboratory of Tissue Homeostasis, Institute for Life and Medical Sciences, Kyoto University
- Rin Mizuno
- Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto University
- Riyo Konishi
- Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto University
- Masaya Onishi
- Graduate School of Frontier Science, The University of Tokyo
- Kyoko Masuda
- Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University
- Yuka Kobayashi
- Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University
- Hiroshi Kawamoto
- Laboratory of Immunology, Institute for Life and Medical Sciences, Kyoto University
- Ayako Suzuki
- Graduate School of Frontier Science, The University of Tokyo
- Chenfeng He
- Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto University
- Yuki Nakamura
- Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto University
- Kosuke Kawaguchi
- Department of Breast Surgery, Kyoto University Graduate School of Medicine
- Masakazu Toi
- Department of Breast Surgery, Kyoto University Graduate School of Medicine
- Masahito Shimizu
- Department of Gastroenterology/Internal Medicine, Gifu University Graduate School of Medicine
- Yasuhito Tanaka
- Department of Gastroenterology and Hepatology, Faculty of Life Sciences, Kumamoto University
- Yutaka Suzuki
- Graduate School of Frontier Science, The University of Tokyo
- Shinpei Kawaoka
- Inter-Organ Communication Research Team, Institute for Life and Medical Sciences, Kyoto University
- DOI
- https://doi.org/10.1038/s42003-023-04479-w
- Journal volume & issue
-
Vol. 6,
no. 1
pp. 1 – 12
Abstract
Spatial transcriptomics reveal how distant cancer affect gene expression and zonation in mouse liver in a manner that differs between biological pathways.