Nanotechnology-Enabled COVID-19 mRNA Vaccines

Yu Gao; Kaiyun Yang; Andrew N. Shelling; Zimei Wu

doi:10.3390/encyclopedia1030059

Encyclopedia (Aug 2021)

Nanotechnology-Enabled COVID-19 mRNA Vaccines

Yu Gao,
Kaiyun Yang,
Andrew N. Shelling,
Zimei Wu

Affiliations

Yu Gao: Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1142, New Zealand
Kaiyun Yang: Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1142, New Zealand
Andrew N. Shelling: Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1142, New Zealand
Zimei Wu: Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1142, New Zealand

DOI: https://doi.org/10.3390/encyclopedia1030059
Journal volume & issue: Vol. 1, no. 3
pp. 773 – 780

Abstract

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COVID-19 mRNA vaccines contain synthetic mRNA sequences encoded for the Spike proteins expressed on the surface of SARS-CoV-2, and utilize the host cells to produce specific antigens that stimulate both humoral and cellular immunities. Lipid nanoparticles are essential to facilitate the intracellular delivery of the mRNA to its action site, the ribosome, to fully exert its effect.

Published in Encyclopedia

ISSN: 2673-8392 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science
Website: https://www.mdpi.com/journal/encyclopedia

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Abstract

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