(1<i>S</i>,1′<i>S</i>)-2,2′-(Benzylazanediyl)bis(1-((3a<i>R</i>,4<i>R</i>,6a<i>R</i>)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethan-1-ol)

Abstract

(1S,1′S)-2,2′-(Benzylazanediyl)bis(1-((3aR,4R,6aR)-2,2-dimethyltetrahydrofuro [3,4 d][1,3]dioxol-4-yl)ethan-1-ol), presenting a tertiary β-aminodiol moiety, was synthesized in 72% yield in a one-step reaction from an aminolysis of an isosorbide-derived oxirane with benzylamine. This β-aminodiol was fully characterized by 1H and 13C NMR and HRMS analyses.

Keywords

• isosorbide
• sustainable material
• ?-aminoalcohol
• ?-aminodiol
• oxirane
• epoxide