Bio-corrosion behaviors and bio-compatibilities of TiNbZrTa and TiNbZrTaMo high entropy alloys

Abstract

The bio-corrosion behavior and bio-compatibility of TiNbZrTa and TiNbZrTaMo high entropy alloys (HEAs) are crucial for their efficient maintenance during biological implantation. In this work, TiNbZrTa and TiNbZrTaMo HEAs were successfully prepared via vacuum melting, with a β-type titanium alloy Ti35Nb7Zr5Ta, exhibiting good biocompatibility used as a comparison. Due to the high entropy effect of equal atomic ratios, both TiNbZrTa and TiNbZrTaMo HEAs exhibit body-centered cubic (BCC) structure and lattice distortion compared to the β titanium alloy Ti35Nb7Zr5Ta. Mo elements contribute to the formation of a new BCC phase, resulting in a white matrix rich in Ta and Mo, and a dark second phase rich in Ti, Zr, and Nb. Electrochemical test results at 37 °C shown that TiNbZrTa has a wider and more stable passivation area than TiNbZrTaMo. The XPS results shown that formation of the passive film is related to the main elements added. Ti, Nb, Ta and Mo formed oxides via the solid-liquid interface and migrate inward, while Zr is formed at the passivation film/metal substrate interface and migrates outward, finally forming the layered structure of the passivation film. Additionally, the cytotoxicity test of mouse fiber cells was carried out to evaluate the biocompatibility of the HEAs. The results shown that the cell proliferation rate of TiNbZrTa and TiNbZrTaMo HEAs reached 0 and 1, respectively, with TiNbZrTa exhibiting better biocompatibility, as adding Mo reduced the cell proliferation rate. These findings may provide a method for predicting the bio-corrosion behavior and bio-compatibility of HEAs used for biological implantation.

Keywords

• Biomaterials
• High entropy alloys
• Vacuum arc-Melting
• Corrosion behaviors
• TiNbZrTaMo