BMC Research Notes (Dec 2011)

Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

  • Manirakiza Alexandre,
  • Boas Susana,
  • Beyam Narcisse,
  • Zadanga Germain,
  • Konamna François,
  • Njuimo Siméon P,
  • Laganier Rémi

DOI
https://doi.org/10.1186/1756-0500-4-543
Journal volume & issue
Vol. 4, no. 1
p. 543

Abstract

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Abstract Background Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. Findings and conclusion The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

Keywords