Magnetic Janus origami robot for cross-scale droplet omni-manipulation

Shaojun Jiang; Bo Li; Jun Zhao; Dong Wu; Yiyuan Zhang; Zhipeng Zhao; Yiyuan Zhang; Hao Yu; Kexiang Shao; Cong Zhang; Rui Li; Chao Chen; Zuojun Shen; Jie Hu; Bin Dong; Ling Zhu; Jiawen Li; Liqiu Wang; Jiaru Chu; Yanlei Hu

doi:10.1038/s41467-023-41092-1

Nature Communications (Sep 2023)

Magnetic Janus origami robot for cross-scale droplet omni-manipulation

Shaojun Jiang,
Bo Li,
Jun Zhao,
Dong Wu,
Yiyuan Zhang,
Zhipeng Zhao,
Yiyuan Zhang,
Hao Yu,
Kexiang Shao,
Cong Zhang,
Rui Li,
Chao Chen,
Zuojun Shen,
Jie Hu,
Bin Dong,
Ling Zhu,
Jiawen Li,
Liqiu Wang,
Jiaru Chu,
Yanlei Hu

Affiliations

Shaojun Jiang: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Bo Li: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China
Jun Zhao: Center of Engineering Technology Research for Biomedical Optical Instrument, Hefei Institutes of Physical Science, Chinese Academy of Sciences
Dong Wu: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Yiyuan Zhang: Department of Mechanical Engineering, The University of Hong Kong
Zhipeng Zhao: Department of Mechanical Engineering, The University of Hong Kong
Yiyuan Zhang: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Hao Yu: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China
Kexiang Shao: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Cong Zhang: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Rui Li: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Chao Chen: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Zuojun Shen: Department of Clinical Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Jie Hu: Department of Clinical Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Bin Dong: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Ling Zhu: Center of Engineering Technology Research for Biomedical Optical Instrument, Hefei Institutes of Physical Science, Chinese Academy of Sciences
Jiawen Li: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Liqiu Wang: Department of Mechanical Engineering, The Hong Kong Polytechnic University
Jiaru Chu: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China
Yanlei Hu: CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China

DOI: https://doi.org/10.1038/s41467-023-41092-1
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 12

Abstract

Read online

Abstract The versatile manipulation of cross-scale droplets is essential in many fields. Magnetic excitation is widely used for droplet manipulation due to its distinguishing merits. However, facile magnetic actuation strategies are still lacked to realize versatile multiscale droplet manipulation. Here, a type of magnetically actuated Janus origami robot is readily fabricated for versatile cross-scale droplet manipulation including three-dimensional transport, merging, splitting, dispensing and release of daughter droplets, stirring and remote heating. The robot allows untethered droplet manipulation from ~3.2 nL to ~51.14 μL. It enables splitting of droplet, precise dispensing (minimum of ~3.2 nL) and release (minimum of ~30.2 nL) of daughter droplets. The combination of magnetically controlled rotation and photothermal properties further endows the robot with the ability to stir and heat droplets remotely. Finally, the application of the robot in polymerase chain reaction (PCR) is explored. The extraction and purification of nucleic acids can be successfully achieved.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal