Association of Various Factors with Thrombocytopenia in Neonates, Secondary to Maternal Pregnancy-Induced Hypertension

Abstract

Objective: To assess the presence of Thrombocytopenia among the neonates born to mothers having pregnancy-induced hypertension and associated socio-demographic factors. Study Design: Cross-sectional study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Apr to Jun 2021. Methodology: This study was conducted on neonates who were born to mothers who were diagnosed and managed with pregnancy-induced hypertension. Thrombocytopenia was defined as a platelet count of <150,000/μl and was performed after 24 hours of birth till seven days of age. Gender of the neonate, Birth weight, gestational age and mode of delivery were the factors studied with Thrombocytopenia in the study population. Results: A total of 300 neonates born to mothers with pregnancy-induced hypertension were included in the study. The mean age of the mothers included in the study was 34.16±2.443 years, while the mean age of the neonates was 3.66±2.33 years. Of them, 90(30%) had the presence of Thrombocytopenia, while 210(70%) had a normal platelet count. 160(53.3%) were male neonates, while 140(46.7%) were female. Low birth weight of neonates and gestational age <37 weeks had a statistically significant relationship (p-value<0.05) with the presence of Thrombocytopenia in neonates born to mothers with pregnancyinduced hypertension. Conclusion: Thrombocytopenia was a common finding among neonates born to mothers who suffered from pregnancyinduced hypertension. Neonates born at less than 37 weeks and those with low birth weight were more at risk of developing Thrombocytopenia as compared to neonates who were born at term with normal weight.

Keywords

• Infant
• Newborn
• Hypertension
• Pregnancy-Induced
• Blood platelets
• Platelet count