In recent years, the number of people driving from plain areas to the western plateau of China has been increasing, and their safety is threatened by acute high-altitude reactions caused by hypoxia. Vehicle-mounted pressure swing adsorption oxygen supply technology can help solve this problem. For the optimization of vehicle pressure swing adsorption oxygen production, the influence of different pressure equalization methods on oxygen production efficiency was studied. The best oxygen production performance was achieved when the initial upper pressure equalization method and the simultaneous pressure equalization method were used. Using a 160 W air compressor, the product gas flow rate could reach 2.5 L/min with an oxygen concentration of 93.48%. The impact of adsorption time, equalization time, flow rate, and throttle inner diameter on oxygen concentration and recovery rate was analyzed using the response surface method. The order of the four factors affecting oxygen concentration is as follows: flow rate > adsorption time > equalization time > throttle inner diameter. After optimization, the product gas flow rate was 2.6 L/min, the oxygen concentration was 92.11%, and the oxygen recovery rate was 44.51%.
