Methylene tetrahydrofolate dehydrogenase 2 (MTHFD2) is overexpressed in head and neck squamous cell carcinoma (HNSCC) and correlated with patient’s poor prognosis

Sun Biqiang; He Zhijun; Liu Gan; Fu Xiao; Chen Zhiyong; Li Guoli

doi:10.1515/pteridines-2020-0033

Pteridines (Dec 2021)

Methylene tetrahydrofolate dehydrogenase 2 (MTHFD2) is overexpressed in head and neck squamous cell carcinoma (HNSCC) and correlated with patient’s poor prognosis

Sun Biqiang,
He Zhijun,
Liu Gan,
Fu Xiao,
Chen Zhiyong,
Li Guoli

Affiliations

Sun Biqiang: School of Pharmacy, Hunan Traditional Chinese Medical College, Zhuzhou, Hunan Province 412012, China
He Zhijun: School of Medicine, Hunan Traditional Chinese Medical College, Zhuzhou, Hunan Province 412012, China
Liu Gan: Department of Otolaryngology and Head Neck, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan Province 410007, China
Fu Xiao: Department of Otolaryngology and Head Neck Surgery, The First Affiliated Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, Hunan Province 412000, China
Chen Zhiyong: Department of Otolaryngology and Head Neck Surgery, The First Affiliated Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, Hunan Province 412000, China
Li Guoli: Department of Otolaryngology and Head Neck Surgery, The First Affiliated Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, Hunan Province 412000, China

DOI: https://doi.org/10.1515/pteridines-2020-0033
Journal volume & issue: Vol. 32, no. 1
pp. 98 – 105

Abstract

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To investigate methylene tetrahydrofolate dehydrogenase 2 (MTHFD2) expression, biological function, and correlation with head and neck squamous cell carcinoma (HNSCC) patient’s prognosis.

Published in Pteridines

ISSN: 0933-4807 (Print); 2195-4720 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Chemistry: Crystallography
Website: https://www.degruyter.com/view/j/pteridines

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Abstract

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