MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila

Xiao Chen; Michael Rosbash

doi:10.1038/ncomms14707

Nature Communications (Mar 2017)

MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila

Xiao Chen,
Michael Rosbash

Affiliations

Xiao Chen: Department of Biology, Howard Hughes Medical Institute and National Center for Behavioral Genomics, Brandeis University
Michael Rosbash: Department of Biology, Howard Hughes Medical Institute and National Center for Behavioral Genomics, Brandeis University

DOI: https://doi.org/10.1038/ncomms14707
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 11

Abstract

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Accumulating evidence suggests that microRNAs play a role in circadian regulation. Here the authors show that in theDrosophila brain, mir-92a suppresses the excitability of PDF neurons—key circadian pacemaker cells in Drosophila—via inhibiting the translation of its target sirt2.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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