Endoscopic characteristics of different grades of melanosis coli complicated with polyps

Abstract

Objective To investigate the endoscopic characteristics of different grades of melanosis coli （MC） complicated with polyps. Methods Clinical and endoscopic data of 597 patients diagnosed with MC who underwent colonoscopy were retrospectively analyzed. The correlation of different grades of MC with age， gender and intestinal diseases was analyzed. The gender， age， polyp size and pathological type of polyps in patients with different grades of MC were analyzed statistically. Results Polyps were more commonly detected in gradeⅠMC than in gradeⅡand gradeⅢMC. The size of polyps significantly differed among different grades of MC. The detection rate of < 0.5 cm polyps in gradeⅢMC was 37.50%， significantly lower than 67.11% in gradeⅠand 60.18% in gradeⅡMC. The detection rate of 0.6-1.0 cm polyps in gradeⅢMC was 57.50%， significantly higher than 23.49% in grade Ⅰand 25.66% in gradeⅡMC. The detection rates of hyperplastic polyps and tubular adenoma significantly differed among different grades of MC complicated with polyp （all P < 0.05）. No statistical significance was observed in the distribution of inflammatory polyp， retention polyp， serrated adenoma and tubular-serrated adenoma among different grades of MC complicated with polyp （all P > 0.05）. Conclusions Polyps are more commonly detected in gradeⅠMC. Polyps of 0.6-1.0 cm in size are more likely to be detected in grade ⅢMC. Hyperplastic polyps are more commonly detected in gradeⅠMC， whereas tubular adenoma in gradeⅡandⅢMC.

Keywords

• melanosis coli|different grades|colorectal polyp|tubular adenoma