1502 Tumor heterogeneity impedes immunotherapy through driving spatially organized pockets of immunosuppression

• Lawrence Fong,
• Alexis Combes,
• Miho Tanaka,
• Lotus Lum,
• Kenneth Ng,
• Zoe Adams,
• Daphne Superville,
• Max Krummel,
• Kenneth Hu,
• Cecilia Ledezma-Soto,
• Bushra Samad,
• Kelly Kersten,
• Melissa Q Reeves

Affiliations

Lawrence Fong

11University of California San Francisco, San Francisco, CA, USA

Alexis Combes

3University of California, San Francisco, San Francisco, CA, USA

Miho Tanaka

University of California, San Francisco, San Francisco, CA, USA

Lotus Lum

University of California, San Francisco, San Francisco, CA, USA

Kenneth Ng

1University of California, San Francisco, San Francisco, CA, USA

Zoe Adams

University of California, San Francisco, San Francisco, CA, USA

Daphne Superville

University of California, San Francisco, San Francisco, CA, USA

Max Krummel

1University of California, San Francisco (UCSF), CA, USA

Kenneth Hu

6University of California, San Francisco, San Francisco, CA, USA

Cecilia Ledezma-Soto

1University of California, San Francisco, San Francisco, CA, USA

Bushra Samad

1University of California, San Francisco, San Francisco, CA, USA

Kelly Kersten

1University of California, San Francisco, San Francisco, CA, USA

Melissa Q Reeves

2University of Utah Huntsman Cancer Institute, Salt Lake City, UT, USA