Are colon neoplastic lesions associated with stomach helicobacter pylori infection?

Abstract

A number of previous studies have shown that there is a correlation between Helicobacter Pylori (H. Pylori) and colorectal neoplasia. However, other studies could not prove whether there is a relation between the H. Pylori infection and the development of neoplastic polyploidy lesions in the colon. The aim of this study was to examine whether there is an in increase in the development of neoplastic lesions in the colon depending on the H. Pylori infection. In this case controlled retrospective study, patients who underwent both endoscopy and colonoscopy at the endoscopy unit of our hospital between January 2012 and January 2013 were evaluated. At colonoscopy, patients without any pathology or whose colon mucosa pathologies were reported as “nonspecific colon mucosa” were classified as the first group (n = 85), and those with one or more than one polyps as the second group (n = 75). The groups were compared in terms of the presence and intensity of H. Pylori, and severity of inflammatory activity and intestinal metaplasia. The results of the two groups were analogous with regard to H. Pylori positivity (p>0.05). No statistical difference was observed between the two groups with respect to H. Pylori intensity and severity of inflammatory activity in the H. Pylori positive patients (p>0.05). In conclusion, no relation between the presence of H. Pylori and the formation of polyp in the colon was found.

Keywords

• Key Words: Helicobacter pylori
• Colonic Polyps
• Neoplasms, Colonic