Obstructive sleep apnea-hypopnea syndrome (OSAHS) and its relation to cancer

Abstract

For some years, it has been suggested that patients with untreated obstructive sleep apnea-hypopnea syndrome are more likely to have solid cancer and increased cancer mortality, although some doubt on the issue has arisen. In consequence, this article describes, on the one hand, the most important studies on the topic and, on the other, the pathophysiology proposed by researchers, who formulate an association in which hypoxia, DNA oxidative damage, endothelial dysfunction and the disruption of the dream architecture play a fundamental role, in addition to other interesting considerations.

Keywords

• Síndromes de la apnea del sueño
• Neoplasias
• Anoxia
• Estrés oxidativo.