Prognostic factors in patients with rheumatoid arthritis: current stage of a problem

Abstract

The basic principles of the diagnostic and treatment of patients with rheumatoid arthritis (RA) has changed in recent years. Last clinical guidelines recommended the initiation of therapy with biologic agents (BA) as early as it possible, however the patient population with RA has heterogeneity of clinical progression. In present review authors analyzed the basic prognostic factors (clinical, immunological, radiological, genetic) that can predict clinical outcomes also in patients with BA therapy.