Imaging of Chemical Reactions Using a Terahertz Chemical Microscope
Toshihiko Kiwa,
Tatsuki Kamiya,
Taiga Morimoto,
Kentaro Fujiwara,
Yuki Maeno,
Yuki Akiwa,
Masahiro Iida,
Taihei Kuroda,
Kenji Sakai,
Hidetoshi Nose,
Masaki Kobayashi,
Keiji Tsukada
Affiliations
Toshihiko Kiwa
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Tatsuki Kamiya
Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Taiga Morimoto
Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Kentaro Fujiwara
Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Yuki Maeno
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Yuki Akiwa
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Masahiro Iida
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Taihei Kuroda
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Kenji Sakai
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
Hidetoshi Nose
Kyowa Fintech Co. Ltd., 948-9 Kanaokanishi, Higashiku, Okayama 704-8193, Japan
Masaki Kobayashi
Kyowa Fintech Co. Ltd., 948-9 Kanaokanishi, Higashiku, Okayama 704-8193, Japan
Keiji Tsukada
Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 3-1-1 Tsushimanaka, Kitaku, Okayama 700-8530, Japan
This study develops a terahertz (THz) chemical microscope (TCM) that visualizes the distribution of chemical reaction on a silicon-based sensing chip. This chip, called the sensing plate, was fabricated by depositing Si thin films on a sapphire substrate and thermally oxidizing the Si film surface. The Si thin film of the sensing plate was irradiated from the substrate side by a femtosecond laser, generating THz pulses that were radiated into free space through the surface field effect of the Si thin film. The surface field responds to chemical reactions on the surface of the sensing plate, changing the amplitude of the THz pulses. This paper first demonstrates the principle and experimental setup of the TCM and performs the imaging and measurement of chemical reactions, including the reactions of bio-related materials.
