BMJ Open (Oct 2020)

Patient characteristics associated with a poor response to non-surgical multidisciplinary management of knee osteoarthritis: a multisite prospective longitudinal study in an advanced practice physiotherapist-led tertiary service

  • Tracy Comans,
  • Shaun O'Leary,
  • Maree Raymer,
  • Peter Window,
  • Patrick Swete Kelly,
  • Bula Elwell,
  • Ian McLoughlin,
  • Will O'Sullivan,
  • Ben Phillips,
  • Anneke Wake,
  • Andrew Ralph,
  • Helen O'Gorman,
  • Ellen Jang,
  • Andrew Hislop,
  • Darryl Lee,
  • Linda Garsden,
  • Daniel Wickins,
  • Michelle Cottrell,
  • Asaduzzaman Khan,
  • Steven McPhail

DOI
https://doi.org/10.1136/bmjopen-2020-037070
Journal volume & issue
Vol. 10, no. 10

Abstract

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Objectives To explore patient characteristics recorded at the initial consultation associated with a poor response to non-surgical multidisciplinary management of knee osteoarthritis (KOA) in tertiary care.Design Prospective multisite longitudinal study.Setting Advanced practice physiotherapist-led multidisciplinary orthopaedic service within eight tertiary hospitals.Participants 238 patients with KOA.Primary and secondary outcome measures Standardised measures were recorded in all patients prior to them receiving non-surgical multidisciplinary management in a tertiary hospital service across multiple sites. These measures were examined for their relationship with a poor response to management 6 months after the initial consultation using a 15-point Global Rating of Change measure (poor response (scores −7 to +1)/positive response (scores+2 to+7)). Generalised linear models with binomial family and logit link were used to examine which patient characteristics yielded the strongest relationship with a poor response to management as estimated by the OR (95% CI).Results Overall, 114 out of 238 (47.9%) participants recorded a poor response. The odds of a poor response decreased with higher patient expectations of benefit (OR 0.74 (0.63 to 0.87) per 1/10 point score increase) and higher self-reported knee function (OR 0.67 (0.51 to 0.89) per 10/100 point score increase) (p<0.01). The odds of a poor response increased with a greater degree of varus frontal knee alignment (OR 1.35 (1.03 to 1.78) per 5° increase in varus angle) and a severe (compared with mild) radiological rating of medial compartment degenerative change (OR 3.11 (1.04 to 9.3)) (p<0.05).Conclusions These characteristics may need to be considered in patients presenting for non-surgical multidisciplinary management of KOA in tertiary care. Measurement of these patient characteristics may potentially better inform patient-centred management and flag the need for judicious monitoring of outcome for some patients to avoid unproductive care.