Investigation into the Influence of the Process Parameters on the Stability of a Poly(Vinyl)-Alcohol-Based Coating System
Viviana Claudia Canale,
Lorenzo Paleari,
Mario Bragaglia,
Greta Petrella,
Leonardo Severini,
Francesca Nanni,
Claudia Mazzuca,
Antonio Palleschi
Affiliations
Viviana Claudia Canale
Department of Chemical Science and Technologies, University of Rome ‘Tor Vergata’, Via della Ricerca Scientifica, 00133 Rome, Italy
Lorenzo Paleari
Department of Enterprise Engineering ‘Mario Lucertini’, University of Rome ‘Tor Vergata’ and INSTM RU Roma-Tor Vergata, Via del Politecnico 1, 00133 Rome, Italy
Mario Bragaglia
Department of Enterprise Engineering ‘Mario Lucertini’, University of Rome ‘Tor Vergata’ and INSTM RU Roma-Tor Vergata, Via del Politecnico 1, 00133 Rome, Italy
Greta Petrella
Department of Chemical Science and Technologies, University of Rome ‘Tor Vergata’, Via della Ricerca Scientifica, 00133 Rome, Italy
Leonardo Severini
Department of Chemical Science and Technologies, University of Rome ‘Tor Vergata’, Via della Ricerca Scientifica, 00133 Rome, Italy
Francesca Nanni
Department of Enterprise Engineering ‘Mario Lucertini’, University of Rome ‘Tor Vergata’ and INSTM RU Roma-Tor Vergata, Via del Politecnico 1, 00133 Rome, Italy
Claudia Mazzuca
Department of Chemical Science and Technologies, University of Rome ‘Tor Vergata’, Via della Ricerca Scientifica, 00133 Rome, Italy
Antonio Palleschi
Department of Chemical Science and Technologies, University of Rome ‘Tor Vergata’, Via della Ricerca Scientifica, 00133 Rome, Italy
Most tablets put on the market are coated with polymers soluble in water. The Opadry II 85 series from Colorcon Inc., is a family of PVA-based products marketed since the 1990s. Despite numerous publications on the properties of PVA, to date, limited work has been undertaken to determine the physico-chemical parameters (i.e., UV light, high temperature, and relative humidity) that could affect the performance of PVA-based coatings. To this end, we performed artificial ageing processes on samples made of Opadry Orange II or of some selected components of this coating and analysed them by means of a multidisciplinary approach, using, for example, FTIR, NMR, rheology, and DMTA measurements. In this way, we analysed the influence of the critical components of the Opadry Orange II formula, such as titanium dioxide and aluminium hydroxide, on the coating characteristics under ageing conditions.
