Identification of Salmonella enterica serovar Typhi strain from a young Brazilian patient: the relevance of automated microbiological methods for the rapid diagnosis of systemic infections

Abstract

Introduction: Latin American countries have public health problems that are aggravated by inadequate basic sanitary conditions. Inefficient vaccination coverage, as well as the fact that a significant portion of the population is exposed to contaminated water and food, can lead to an increase in the incidence of some diseases. Methodology: the work reports a case of infection by Salmonella enterica serovar Typhi (S. Typhi), whose contagion is strictly related to personal and environmental hygiene conditions. Conclusion: accurate identification and immediate detection of the etiologic agent using automated methods, such as Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) and the BACT / ALERT System® 3D, can positively contribute to the patient's prognosis and therapeutic success. Thus, principally in the Latin American, a quick and adequate treatment is of great importance, both for the patient and to minimize the spread of multidrug-resistant strains and the consequent reduction of therapeutic options.

Keywords

• Salmonellosis
• Salmonella Typhi
• Typhoid fever
• MALDI-TOF MS
• Blood culture