Indian Journal of Endocrinology and Metabolism (Jan 2013)

Renal phosphate handling: Physiology

  • Narayan Prasad,
  • Dharmendra Bhadauria

DOI
https://doi.org/10.4103/2230-8210.113752
Journal volume & issue
Vol. 17, no. 4
pp. 620 – 627

Abstract

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Phosphorus is a common anion. It plays an important role in energy generation. Renal phosphate handling is regulated by three organs parathyroid, kidney and bone through feedback loops. These counter regulatory loops also regulate intestinal absorption and thus maintain serum phosphorus concentration in physiologic range. The parathyroid hormone, vitamin D, Fibrogenic growth factor 23 (FGF23) and klotho coreceptor are the key regulators of phosphorus balance in body.

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