Adult Testicular Non-Hodgkin’s Lymphoma: A Rare Case Series

Abstract

To evaluate the clinicopathological profiles of patients presenting with testicular lymphomas. In our study from February 2020 to August 2023, 6 rare cases of testicular non hodgkin’s lymphomas were diagnosed in a three and a half year period and were divided based on primary or secondary involvement. Immunohistochemistry (IHC) was performed on all cases and results were compared based on clinicopathological profile. The mean age was 57 years. Most common presenting complaint was unilateral or bilateral testicular swelling, associated with pain in some cases. B symptoms were present only in one case. Out of 6 cases, 3 showed primary involvement and 3 were secondarily involved. On applying IHC, 3 cases were diagnosed as Diffuse Large B-Cell Lymphoma (DLBCL), Non-Germinal Centre subtype and 3 as DLBCL, Germinal Centre subtype.Testicular lymphomas are rare highly malignant tumors and pose a strong diagnostic difficulty for both clinician and pathologist. Hence, clinical suspicion should always be maintained in cases of testicular swelling for proper workup of the patient. Keywords: Testicular lymphoma, Diffuse large B-cell lymphoma, Testis, Extranodal