Marine Nucleosides: Structure, Bioactivity, Synthesis and Biosynthesis
Ri-Ming Huang,
Yin-Ning Chen,
Ziyu Zeng,
Cheng-Hai Gao,
Xiangdong Su,
Yan Peng
Affiliations
Ri-Ming Huang
Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China
Yin-Ning Chen
College of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China
Ziyu Zeng
School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Cheng-Hai Gao
Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences, Nanning 530007, China
Xiangdong Su
Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK
Yan Peng
Life Science & Technology School, Lingnan Normal University, Zhanjiang 52048, China
Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.
