Transplantation of intestinal microbiota

Abstract

The results are presented of evaluation of the efficiency of the filtered aqueous suspension of white mice (donors) feces and microorganisms of indigenous microflora in the correction of intestinal microbiocenosis of conventional white mice with antibiotic-associated dysbacteriosis with administration of suspension and microorganisms per os and per rectum. After the start of administration of suspension and microorganisms of fecal microflora to experimental animals the dynamics of the total content of microorganisms and the number of some representatives of intestinal microflora in 1 g of feces were evaluated in comparison with self-recovery of intestinal microflora in the control group animals. Results showed that the supernatant of an aqueous suspension of white mice (donors) feces, containing microbial exometabolites and other biologically active compounds, has in a short time the most pronounced effect on the recovery of the normal intestinal microflora in experimental animals.

Keywords

• экзометаболиты
• кишечная микрофлора
• дисбактериоз
• трансплантация кишечной микробиоты